Research Interests

The overarching goal of our lab is to understand the molecular mechanisms responsible for the decline in neural stem cell function with age. Neural stem cells have the capacity to give rise to new neurons in the adult brain, including in aged individuals. However, an age-related depletion of the NSC reservoir and a decrease in new neuron formation accompany the emergence of cognitive deficits during aging. We are interested in discovering the genes and transcriptional networks that are responsible for this deterioration, with the long term goal of identifying strategies that slow or reverse it.

To learn more about the exciting aging research going on at Brown University, check out the Brown Biology of Aging Initiative website.

To learn more about neuroscience research at Brown, check out the Brown Institute for Brain Science website.

The Webb Lab is part of the MCB and Neuroscience Graduate Programs at Brown University.